Metabolicledger

Metabolic Ledger (metabolicledger.com), published by Metabolic Ledger Publishing LLC — Rebased monthly GLP-1 cash-price index: the median monthly cash price across a fixed basket of US provider/manufacturer price concepts, indexed to 100 at the earliest period so movements are readable as a series rather than sticker prices. Published as multiple parallel series (all GLP-1 monthly cash; compounded all; compounded semaglutide; compounded tirzepatide; brand NovoCare/LillyDirect) with index value, median, mean, constituent count and month-over-month and quarter-over-quarter change. The basket it…

Metabolicledger offers (Alternative, Price) — Very small by design — a fixed basket of 6 priced constituents in October 2026 feeding 5 published series, refreshed once monthly, with 4 populated index points implied by the reported quarter-over-quarter change (~4-6 months of history). Annual growth at current basket size is on the order of 72 constituent-observations plus 60 series points per year.

GLP-1 affordability time-series for macro and policy reporting (the rebased-index format is what journalists and economists consume rather than raw price tables); manufacturer-savings-program effectiveness measurement by comparing savings-card out-of-pocket prices against list and compounded prices inside one comparable series; channel-substitution tracking between manufacturer direct-pay and compounded telehealth; index construction for downstream composite affordability measures; alerting on price moves (the site itself runs a weekly price-move alert)

Coverage spans US; Pharmaceutical Companies, Health Care Services; alternative, price; equities.